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Rapamycin for Dogs: What the Dog Aging Project Reveals (2025 Guide)

Rapamycin & The Dog Aging Project: What We Know So Far (2025) Updated: September 2025 · Reading time: ~7 min A concise guide to rapamycin for dogs: what the Dog Aging Project is studying, safety considerations, and what pet parents can do right now—plus curated links to gene testing, supplement options, and LOY trial overviews. Key Takeaways Rapamycin targets the mTOR pathway and is being studied for extending healthspan in dogs. The Dog Aging Project is evaluating dose, safety, and potential multi-system benefits over time. Until results are conclusive, focus on weight/activity, DNA risk screening , and evidence-based supplements. What Is Rapamycin? Dog Aging Project: Where Evidence Stands Safety, Side Effects, and Vet Checkpoints What You Can Do Right Now Related Reading (Internal Hub) FAQ References What Is Rapamycin? Rapamycin is an mTOR pathwa...
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Rapamycin & The Dog Aging Project: What We Know So Far

Rapamycin & The Dog Aging Project: What It Could Mean for Senior Dogs TL;DR — What you’ll get: What rapamycin is and why it’s linked to longevity research. What the Dog Aging Project is studying in real companion dogs. A vet-friendly checklist to discuss before considering any future trial or product. Related: LOY-003 Pill (Next-Gen) Free PDF: Dog DNA Tests Rapamycin is a medication that suppresses the mTOR pathway—one of the body’s key nutrient-sensing switches linked to aging. In lab animals, carefully controlled doses have been associated with longer, healthier lifespans. The Dog Aging Project (DAP) is a large, ongoing scientific effort asking a simple, high-impact question: “Can we safely slow aging in real pet dogs?” What is Rapamycin? Rapamycin (also called sirolimus) has been used in human medicine for decades. In longevity resear...
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Meet the Company Extending Dog Lifespans: Inside Loyal & Others

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🐾 Longevity Series #2: Meet the Company Extending Dog Lifespans: Inside Loyal & Others Imagine a future where your dog could live not just to 15, but to 25 or even 30. That future may be closer than we think, thanks to pioneering companies like Loyal . 🔬 What is Loyal? Loyal is a biotechnology startup focused exclusively on canine longevity. Backed by investors like Khosla Ventures and operating under veterinary FDA approval pathways, Loyal is currently testing drugs designed to extend both the lifespan and healthspan of dogs—especially large breeds, which tend to age faster. 🌍 Global Interest in Dog Longevity It’s not just Loyal. Other companies and labs in Europe and Asia are entering the longevity biotech space. Whether through gene therapy, anti-aging molecules, or stem cell research, the race to unlock extended vitality in pets is heating up. 💬 What Vets Say Veterinarians are cautiously optimistic. While they stress ...
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